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  • Title: Anencephaly and maternal common cold.
    Author: Kurppa K, Holmberg PC, Kuosma E, Aro T, Saxén L.
    Journal: Teratology; 1991 Jul; 44(1):51-5. PubMed ID: 1957263.
    Abstract:
    To study the risk of anencephaly related to common cold during pregnancy, a case-control study was made. The series comprised 393 Finnish mothers of anencephalic children and their time-area-matched controls in the period 1964 through 1982. Seventy mothers of anencephalic infants and 17 controls had reported common cold in the first trimester [adjusted odds ratio 4.5; 95% confidence interval (2.2-9.1)]. Reported common cold in the second trimester was not associated with anencephaly. As suggested by our previous cohort study in the same population, a true viral influenza resembling "common cold" might not explain the observed association.
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