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  • Title: A cylindrical extracranial cranial base neurinoma of the hypoglossal nerve: a rare tumor with a rare localization: case report.
    Author: Heiroth HJ, Riemenschneider MJ, Steiger HJ, Hänggi D.
    Journal: Neurosurgery; 2009 Jul; 65(1):E212-3; discussion E213. PubMed ID: 19574804.
    Abstract:
    OBJECTIVE: Neurinomas of the hypoglossal nerve are very rare. They are mostly located intracranially or combined intra- and extracranially, resulting in the so-called dumbbell shape. The isolated extracranial localization of the neurinoma of the hypoglossal nerve adjacent to the cranial base as described in this case report is extremely rare. CLINICAL PRESENTATION: The 23-year-old patient presented with recurring headaches. She had right-sided hypoglossal nerve palsy for approximately 5 to 6 years. Magnetic resonance imaging revealed an extracranial tumor with contact to the cranial base originating from the hypoglossal nerve. INTERVENTION: The tumor was extirpated surgically and verified histologically as a schwannoma of the hypoglossal nerve. CONCLUSION: Pathologies of the hypoglossal nerve as such are very rare within the clinical landscape. When a tumor occurs, its shape and location must be analyzed to establish whether, or by which approach, surgical removal is feasible. Although very unusual, the mere extracranial occurrence of a hypoglossal neurinoma at the cranial base should be considered a differential diagnosis.
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