These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Blastic plasmacytoid dendritic cell neoplasm: two cases report and review of literatures].
    Author: An G, Qi JY, Zou DH, Zhao YZ, Chen HS, Qiu LG.
    Journal: Zhonghua Nei Ke Za Zhi; 2009 Mar; 48(3):189-92. PubMed ID: 19576083.
    Abstract:
    OBJECTIVE: To identify the clinical and pathological features of blastic plasmacytoid dendritic cell neoplasm (BPDC). METHODS: The characteristics of BPDC hematodermic neoplasm were discussed with a report of two new cases and review the literatures. RESULTS: Both patients presented with skin nodules and the tumors were CD(4)(+) and CD(56)(+). Lineage specific markers for B- and T-cell were negative and the tumors did not express myeloperoxidase. Systemic chemotherapy resulted in complete remission, but the disease relapsed quickly and were unresponsive to further chemotherapy. The patients died 26 months and 11 months respectively after diagnosis. CONCLUSION: BPDC hematodermic neoplasm is a rare subtype of lymphoma with distinct clinicopathologic and immunophenotypic features. The disease often has a fulminant course with a poor prognosis. More recent studies suggest that there is a derivation from a plasmacytoid dendritic cell precursor.
    [Abstract] [Full Text] [Related] [New Search]