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  • Title: Hemicraniectomy for malignant middle cerebral artery infarction.
    Author: Köhrmann M, Schwab S.
    Journal: Curr Opin Crit Care; 2009 Apr; 15(2):125-30. PubMed ID: 19578323.
    Abstract:
    PURPOSE OF REVIEW: Space-occupying, malignant hemispheric infarction is one of the most devastating forms of ischemic stroke. Several case series had suggested decompressive hemicraniectomy as a life-saving therapy, but, until recently, there was no proof for this procedure from randomized controlled trials. RECENT FINDINGS: In 2007, results from a pooled analysis of three European trials as well as data from two of these trials were published and yield compelling evidence for the benefit of hemicraniectomy. SUMMARY: Data from the published trials leave no doubt about the benefit especially the life-saving character of hemicraniectomy for malignant hemispheric infarction. However, some open questions (i.e. timing of surgery, age limit for hemicraniectomy) remain to be answered in the future.
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