These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Palladium-catalyzed decarboxylative arylation of C-H bonds by aryl acylperoxides.
    Author: Yu WY, Sit WN, Zhou Z, Chan AS.
    Journal: Org Lett; 2009 Aug 06; 11(15):3174-7. PubMed ID: 19583200.
    Abstract:
    A Pd(OAc)(2)-catalyzed protocol for decarboxylative arylation of aromatic C-H bond was developed using aryl acylperoxides as inexpensive aryl sources. Substrates containing pyridyl, oxime, and oxazoline groups undergo effectively ortho-selective C-H arylation with excellent functional group tolerance. This arylation should begin by directing-group-assisted cyclopalladation, followed by the reaction of the palladacycle with aryl radicals generated in situ by thermal decomposition of the peroxides.
    [Abstract] [Full Text] [Related] [New Search]