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  • Title: Essential oil of Lindera neesiana fruit: chemical analysis and its potential use in topical applications.
    Author: Comai S, Dall'Acqua S, Grillo A, Castagliuolo I, Gurung K, Innocenti G.
    Journal: Fitoterapia; 2010 Jan; 81(1):11-6. PubMed ID: 19586610.
    Abstract:
    The composition of the essential oil of Lindera neesiana Kurz fruit was examined by GC-MS, (1)H, (13)C and bidimensional NMR techniques (HMQC, HMBC, COSY, TOCSY). Forty compounds were identified, representing approximately 86% of the oil: Z-citral (15.08%), E-citral (11.89%), eucalyptol (8.75%), citronellal (6.72%), alpha-pinene (6.63%) and beta-pinene (5.61%) were the major components. The essential oil of L. neesiana fruit showed significant antimicrobial activity against Staphylococcus aureus and Candida albicans at non-cytotoxic doses in human keratinocytes, suggesting possible topical applications. GRAPHICAL ABSTRACT: The essential oil of Lindera neesiana was investigated by GC-MS and NMR techniques. Its biological activities suggest possible topical applications.
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