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  • Title: [An analysis on prognostic factors of hilar cholangiocarcinoma].
    Author: Zhou LX, Zhang ZW, Xu ZY.
    Journal: Zhonghua Yi Xue Za Zhi; 2009 May 12; 89(18):1275-7. PubMed ID: 19595185.
    Abstract:
    OBJECTIVE: To investigate the influencing factors on the prognosis of hilar cholangiocarcinoma. METHODS: The clinical data were retrospectively analyzed in 86 cases of hilar cholangiocarcinoma admitted into our hospital from Jan. 2004 to July. 2008. RESULTS: Of 86 cases with hilar cholangiocarcinoma, the mean survival time was 13.7 +/- 2.3 months, 1-year survival 57.3% and 3-year survival 29.7%. The mean survival time in patients with resection operation (19.4 +/- 2.2 months) was significantly longer than those with no operation (7.2 +/- 1.2 months) (P < 0.05). The mean survival time in patients with non-vascular resection group (23.4 +/- 2.1 months) was significantly longer than those with portal vein resection alone group (15.3 +/- 1.4 months) and hepatic artery resection group (9.3 +/- 0.9 month) (P < 0.05). Cox regression analysis showed that staging, tumor diameter and operative were the dependent prognosis factors while pathologic type, vascular resection and age not the dependent prognosis factors. CONCLUSION: The prognosis of hilar cholangiocarcinoma correlates with operative approach, clinical stage and tumor diameter. A surgeon must be cautious to choose the surgical approach for treatment.
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