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Title: Isoplatensimycin: Synthesis and biological evaluation. Author: Jang KP, Kim CH, Na SW, Kim H, Kang H, Lee E. Journal: Bioorg Med Chem Lett; 2009 Aug 15; 19(16):4601-2. PubMed ID: 19604693. Abstract: Isoplatensimycin, a novel analog of platensimycin, was synthesized via intramolecular dipolar cycloaddition of a carbonyl ylide. Isoplatensimycin showed little activities against strains of Staphylococcus aureus, but exhibited activities against some vancomycin-resistant enteroccoci.[Abstract] [Full Text] [Related] [New Search]