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  • Title: Synchronous renal cell carcinoma and clear cell hepatocellular carcinoma mimicking metastatic disease.
    Author: Hou TC, Wu CC, Yang CR, Wang J.
    Journal: Pathol Res Pract; 2010 May 15; 206(5):342-5. PubMed ID: 19608351.
    Abstract:
    Double carcinomas of hepatocellular and renal cell carcinoma (RCC) are extremely rare, and among the reported cases, none of the hepatocellular carcinomas show clear cell change. We report a case of synchronous double primary clear cell tumor in the liver and the kidney of a 70-year-old male. The renal mass was a renal cell carcinoma of mixed clear and granular cell types, and the hepatic mass was a hepatocellular carcinoma with extensive clear cell change that mimicked a metastatic renal cell carcinoma. A simple battery of immunohistochemical stains composed of hepatocyte antigen, and CD10 was performed to make a definite diagnosis.
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