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  • Title: Safety, efficacy & recurrence rates of imiquimod cream 5% for treatment of anogenital warts.
    Author: Diamantis ML, Bartlett BL, Tyring SK.
    Journal: Skin Therapy Lett; 2009 Jun; 14(5):1-3, 5. PubMed ID: 19609471.
    Abstract:
    Imiquimod 5% cream (Aldara, Graceway Pharmaceuticals) is an immune response modifier used for the topical treatment of anogenital warts in non-HIV-infected patients. Several randomized controlled trials have demonstrated that imiquimod 5% cream is a safe and efficacious treatment. Current data regarding efficacy shows that complete clearance of warts occurred in up to 50% of patients treated with imiquimod 5% cream applied once-daily, 3 times per week for up to 16 weeks. Recurrence rates ranged from up to 19% at 3 months to 23% at 6 months. Imiquimod 5% cream showed an acceptable safety profile; local inflammatory reactions were the most frequent adverse effects, with local erythema being the most common.
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