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  • Title: [Atheromatous material mobilization syndrome after thrombolytic therapy with streptokinase in acute myocardial infarct].
    Author: Arpesani A, Beretta L, Giorgetti PL, Varesi C, Matturri L.
    Journal: Minerva Cardioangiol; 1991 Jun; 39(6):251-4. PubMed ID: 1961445.
    Abstract:
    Streptokinase fibrinolysis is a widely accepted and applied therapy in acute myocardial infarction with good clinical and ECG results. Nevertheless this therapy is not devoid of complications that sometimes can be very serious. In this paper the Authors report the case of a patient 52 years old who has been treated with streptokinase for an acute myocardial infarction with good ECG results but that about eight hours later showed an important cholesterol embolization syndrome with visceral and lower extremity lesions. The patient died about 36 hours later. The Authors emphasize the necessity to exclude aortic aneurysm before using thrombolytic agents and to evaluate carefully the possibility to abstain from this procedure in the presence of certain aneurysmal lesions.
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