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  • Title: Low-grade myofibroblastic sarcoma of the oral cavity.
    Author: Demarosi F, Bay A, Moneghini L, Carrassi A.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Aug; 108(2):248-54. PubMed ID: 19615664.
    Abstract:
    Two cases of low-grade myofibroblastic sarcoma (LGMS) are presented: one of lateral tongue, the other of lower buccal vestibule. LGMS represents a distinct atypical myofibroblastic tumor that occurs in several sites, primarily within the head and neck regions. A painless, enlarging mass is the most common clinical presentation, but a definitive diagnosis requires both histopathological and immunohistochemical analyses. Histologically, LGMS commonly presents as a cellular lesion composed of spindle-shaped tumor cells arranged primarily in fascicles with a diffusely infiltrative pattern. Immunohistochemically, LGMS shows positive staining for at least one myogenic marker, such as desmin, and muscle actin.
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