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  • Title: Impact of allogeneic 2-RBC apheresis on iron stores of Brazilian blood donors.
    Author: Mendrone A, Arrais CA, Almeida Neto C, Gualandro Sde F, Dorlhiac-Llacer PE, Chamone Dde A, Sabino EC.
    Journal: Transfus Apher Sci; 2009 Aug; 41(1):13-7. PubMed ID: 19615943.
    Abstract:
    One limiting factor for automated two-red blood cells collections (2-RBC) is its potential iron depletion. We analyzed hematological parameters and iron balance before, two and four months after 2-RBC of 96 non-supplemented male donors. Four months after 2-RBC, ferritin level was significantly lower (P<0.01) than baseline levels and the number of donors who presented ferritin <30 ng/ml increased from 18 to 47. We concluded that four months was not sufficient for iron recuperation in the population studied. In an attempt to avoid iron depletion after 2-RBC, we recommend augmentation in the interval between blood donations and pre-donation ferritin measurement.
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