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  • Title: Treatment of a case of pediatric hypereosinophilic syndrome with anti-interleukin-5.
    Author: Mehr S, Rego S, Kakakios A, Kilham H, Kemp A.
    Journal: J Pediatr; 2009 Aug; 155(2):289-91. PubMed ID: 19619754.
    Abstract:
    We report the use of anti-interleukin-5 (mepolizumab) during an 18-month period in a pediatric hypereosinophilic syndrome. Infusions every 3 months allowed better control of hypereosinophilic syndrome flares and maintained blood eosinopenia with significantly less steroid use compared with all other therapies (prednisolone alone, interferon alpha, or imatinib mesylate).
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