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  • Title: Does fetal fibronectin testing change patient management in women at risk of preterm labour?
    Author: Bolt LA, Chandiramani M, De Greeff A, Seed P, Shennan AH.
    Journal: Eur J Obstet Gynecol Reprod Biol; 2009 Oct; 146(2):180-3. PubMed ID: 19619930.
    Abstract:
    OBJECTIVE: To determine clinicians' indications for, and actions following, fetal fibronectin testing in both symptomatic and asymptomatic women between 23(+0) and 34(+6) weeks' gestation. STUDY DESIGN: Following clinician education of the predictive ability of fetal fibronectin testing, results of all fetal fibronectin tests done at St Thomas' Hospital over a 6-week period were analysed. Clinicians were asked if the result changed management and if a reciprocal result would have altered management. RESULTS: Ninety-seven fetal fibronectin tests were conducted of which 21 (22%) were positive. Follow-up was done for 91 tests of which 25 (28%) test results directly changed management; 81 (89%) test results had the potential to change management independent of the test result. CONCLUSION: The results of fetal fibronectin testing directly influenced management in a significant number of patients. A large number of women were asymptomatic at testing. Fetal fibronectin testing could be offered more widely and has the potential to benefit patient management.
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