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  • Title: Treatment of concomitant gastric varices in patients with hepatocellular carcinoma at a single Japanese institute.
    Author: Nanashima A, Sumida Y, Abo T, Shibata K, Tomoshige K, Takeshita H, Hidaka S, Fukuoka H, Mochinaga K, Sawai T, Yasutake T, Nagayasu T.
    Journal: Hepatogastroenterology; 2009; 56(91-92):857-60. PubMed ID: 19621717.
    Abstract:
    Hepatocellular carcinoma (HCC) patients often have esophagogastric varices due to portal hypertension by chronic hepatitis or cirrhosis. Surgical treatment for gastric varices is necessary when the patient undergoes hepatic resection for HCC, simultaneously. We examined the clinical demographics, surgical records and outcome in 7 patients undergoing both hepatectomy and Hassab's operation (=decongestion of upper gastric veins and splenectomy) between 1994 and 2007. All patients had HCC, including chronic injured liver diseases. Preoperative liver functions were well preserved in all patients. Right hepatectomy was performed in two patients and limited resections in 5. Three patients had postoperative complications and the in-hospital death by hepatic failure was observed in one. Four patients had tumor recurrence within one year and 3 were dead, while, two patients had long-term survival with or without recurrence of HCC. Following Hassab's operation, gastric varices dramatically disappeared. Portal hypertension and hypersplenism were significantly improved. Simultaneous operation with Hassab's procedure and hepatectomy is useful and can be safely performed in HCC patients with gastric varices.
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