These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Acute retinal necrosis: a case series with clinical features and treatment outcomes.
    Author: Sims JL, Yeoh J, Stawell RJ.
    Journal: Clin Exp Ophthalmol; 2009 Jul; 37(5):473-7. PubMed ID: 19624343.
    Abstract:
    PURPOSE: To determine clinical features, viral aetiology and treatment outcomes of eyes with acute retinal necrosis (ARN). METHODS: Retrospective, interventional, non-comparative case series. RESULTS: Twenty-two patients (23 eyes) were identified between 1996 and 2007. Varicella zoster virus was the causative agent in 12 patients (nine confirmed by polymerase chain reaction), herpes simplex virus type 1 in six (five polymerase chain reaction-confirmed) and unknown in three patients. Five patients had documented herpes zoster infection in the month prior to the onset of ARN. Twelve patients (55%) had identifiable (clinical or subclinical) immune dysfunction. At 6 months, 3 out of 15 eyes (20%) maintained vision 6/12 or better and 7 (47%) were 6/60 or worse. Median final VA was 6/60. Nine eyes developed retinal detachment and two-thirds of these had received prior barrier laser. Poor prognostic factors for severe visual loss by univariate analysis were male gender (P = 0.019), and the development of retinal detachment (P = 0.05). Delay between onset of symptoms and diagnosis was associated with moderate visual loss (P = 0.018). Barrier laser did not reduce the risk of retinal detachment. CONCLUSIONS: Acute retinal necrosis still has poor visual prognosis. Early diagnosis and initiation of treatment may improve outcome.
    [Abstract] [Full Text] [Related] [New Search]