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  • Title: Plasmid-mediated quinolone resistance in Salmonella isolated from patients with overseas travelers' diarrhea in Japan.
    Author: Taguchi M, Kawahara R, Seto K, Inoue K, Hayashi A, Yamagata N, Kamakura K, Kashiwagi E.
    Journal: Jpn J Infect Dis; 2009 Jul; 62(4):312-4. PubMed ID: 19628914.
    Abstract:
    Twenty-eight of the 302 Salmonella strains isolated from patients with overseas travelers' diarrhea who were examined at Kansai Airport Department Station during the 6-year period between 2001 and 2007 showed decreased susceptibility to both nalidixic acid (NA) and ciprofloxacin (CPFX) (MIC of NA, 16-64 microg/mL; MIC of CPFX, 0.064-2.0 microg/mL). These 28 strains revealed no variations in the quinolone resistance-determining region; however, 25 of the strains showed retention of the qnr gene. The qnr-retaining Salmonella belonged to 6 serotypes, and 21 and 4 of the 25 strains showed qnrS1 and qnrS2, respectively. The most common serovar was S. Corvallis (17 strains).
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