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  • Title: Chemical constituents investigation of Daphne tangutica.
    Author: Pan L, Zhang XF, Deng Y, Zhou Y, Wang H, Ding LS.
    Journal: Fitoterapia; 2010 Jan; 81(1):38-41. PubMed ID: 19631260.
    Abstract:
    A phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Two compounds out of these isolates are new daphne diterpene analogs, and their structures were established as 1,2 alpha-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, and 1,2 beta-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, respectively, on the basis of spectroscopic methods. Additionally, this is the first time that 13 known compounds have been isolated and identified from this traditional Tibetan medicinal plant.
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