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  • Title: [Chemotherapeutic pathomorphosis of breast cancer].
    Author: Frank GA, Volchenko NN, Borisov VI.
    Journal: Sov Med; 1990; (11):14-6. PubMed ID: 1963707.
    Abstract:
    Features of pathomorphism of mammary carcinoma were studied in 177 women after a course of drug therapy. Qualitative and quantitative morphologic changes in the tumor were poorly manifest: they were detected in only 54 percent of patients and only in 9 percent the effect was manifest (third-fourth stage of involvement). Characteristic findings here were augmentation of cellular dystrophy, necrotic changes, enhanced nuclear polymorphism; significant injury to tumor parenchyma was paralleled by development of xanthomatosis foci and lymphoid histiocytic infiltration.
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