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  • Title: Accuracy of noninvasive coronary stenosis quantification of different commercially available dedicated software packages.
    Author: Dikkers R, Willems TP, de Jonge GJ, Marquering HA, Greuter MJ, van Ooijen PM, van der Weide MC, Oudkerk M.
    Journal: J Comput Assist Tomogr; 2009; 33(4):505-12. PubMed ID: 19638840.
    Abstract:
    PURPOSE: The purpose of this study was to investigate the noninvasive quantification of coronary artery stenosis using cardiac software packages and vessel phantoms with known stenosis severity. MATERIALS AND METHODS: Four different sizes of vessel phantoms were filled with contrast agent and scanned on a 64-slice multidetector computed tomography. Diameter and area stenosis were evaluated by 2 observers blinded from the true measures using 5 different software packages. Measurements were compared with the true measure of the vessel phantoms. The absolute difference in stenosis measurements and intraobserver and interobserver variabilities were assessed. RESULTS: All software packages show a trend toward larger differences for the smaller vessel phantoms. The absolute difference of the automatic measurements was significantly higher compared with that of the manual measurements in all 5 evaluated software packages for all vessel phantoms (P < 0.05). CONCLUSION: Manual stenosis measurements are significantly more accurate compared with automatic measurements, and therefore, manual adjustments are still essential for noninvasive assessment of coronary artery stenosis.
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