These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effective dilation of small-bowel strictures by double-balloon enteroscopy in patients with symptomatic Crohn's disease (with video).
    Author: Despott EJ, Gupta A, Burling D, Tripoli E, Konieczko K, Hart A, Fraser C.
    Journal: Gastrointest Endosc; 2009 Nov; 70(5):1030-6. PubMed ID: 19640518.
    Abstract:
    BACKGROUND: Crohn's disease (CD)-related small-bowel strictures remain a major cause of morbidity, frequently requiring surgery. OBJECTIVE: Assessment of the feasibility and effectiveness of CD small-bowel stricture dilation by DBE. DESIGN: Prospective case series. SETTINGS: Single, tertiary referral center. METHODS: Outcome data on cases of DBE-assisted CD small-bowel stricture dilation were prospectively collected from 2005. Dilation was performed by using controlled radial expansion balloon dilators. A 10-cm visual analogue scale (VAS) was used to assess obstructive symptoms and dietary restriction before DBE stricture dilation and at follow-up. RESULTS: A total of 13 DBEs were performed in 11 consecutive patients (mean +/- SD age 46.4 +/- 7.8 years). Eighteen small-bowel stricture dilations were performed in 9 of 11 patients. The mean dilation diameter was 15.4 mm (range 12-20 mm). In 2 cases, stricture dilation was not performed because adhesions made reaching the strictures impossible. One case was complicated by a delayed perforation. In the other 8 patients, stricture dilation was successful; VAS scores improved dramatically and none of the patients has required surgery (mean follow-up 20.5 months; range 2-41 months). During follow-up, 2 patients required repeated dilation (at 6.5 and 13 months, respectively) because of symptom recurrence. Clinical improvements in before and after VAS scores were significant (mean 8.8 vs 1.8, respectively; P < .001). LIMITATIONS: Small case series; single tertiary referral center. CONCLUSION: DBE-assisted small-bowel stricture dilation for selected patients with CD is potentially of significant benefit and should be considered as a useful and effective alternative to surgery. Larger studies are required to confirm this benefit.
    [Abstract] [Full Text] [Related] [New Search]