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  • Title: Motor cortical epilepsia partialis continua in a patient with a localized sensory cortical lesion.
    Author: Nakatani-Enomoto S, Terao Y, Hanajima R, Matsuda S, Ohminami S, Inomata-Terada S, Matsumoto H, Yugeta A, Yamamoto T, Goto J, Yumoto M, Tsuji S, Ugawa Y.
    Journal: Clin Neurol Neurosurg; 2009 Nov; 111(9):762-5. PubMed ID: 19647931.
    Abstract:
    We describe a 33-year-old man with cyclosporine encephalopathy who showed continuous jerking in the left upper limb due to epilepsia partialis continua. Jerk-locked back averaging (JLA) of magnetoencephalogram disclosed a spike preceding the jerk localized at the hand motor area, whereas JLA of electroencephalogram revealed no premyoclonus spikes. The paired-pulse motor cortical transcranial magnetic stimulation revealed motor cortical hyperexcitability, while the paired-pulse somatosensory evoked potential showed no sensory cortical hyperexcitability. The brain MRI showed a high intensity lesion localized at the hand sensory area. These results suggest that the jerks were produced by discharges at the motor cortex probably disinhibited by the sensory cortical lesion.
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