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  • Title: [Detection of anti-cytomegalovirus antibodies: comparison of 3 commercial methods].
    Author: García-Aguayo JM.
    Journal: Sangre (Barc); 1990 Dec; 35(6):475-6. PubMed ID: 1965060.
    Abstract:
    A group of 188 sera from pregnant women was screened for cytomegalovirus (CMV) antibodies by immunofluorescence assay (IFA), enzyme immunoassay (EIA), and passive latex agglutination (LA) tests. There were 178 (94.6%) sera for which there was complete agreement between the three tests. One hundred-sixty three sera were positive by two or more methods and judged to be true positives. Accordingly, the highest sensitivity was shown by the EIA and LA tests (100% in both cases). The sensitivity of IFA test was similar (97%). A ranking for technical demand, hands-on time, turnaround time, requirement for special equipment and objectivity sharply favoured the LA test.
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