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  • Title: [The action of tropic adenohypophyseal hormones when administered intraventricularly on rat behavioral reactions].
    Author: Sapronov NS, Kudriashova MF.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1990; 40(6):1158-64. PubMed ID: 1965259.
    Abstract:
    In experiments on rats the influence was studied of tropic hormones of adenohypophysis--somatotropin, thyrotropin and adrenocorticotropin (STH, ThTN and ACTH respectively) on the elaboration and extinction of conditioned reaction of active avoidance (CRAA) in Y-maze and behaviour in the open field under microinjections of hormones into the brain lateral ventricle (0.001-0.002 ME). It has been shown that all studied hormones improve animals learning at negative pain reinforcement; ThTH and ACTH retard it in contrast to STH, which accelerates the extinction of the elaborated CRAA; tropic hormones exert differentiated influence on rats behaviour in the open field. No distinct correlation was found between behavioural manifestation and the level of catecholamines in the rats hypothalamus.
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