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  • Title: [Pathognomonic signs of human papillomavirus infection in diagnostic material from the uterine cervix].
    Author: Isakova LM, Ganina KP, Ivanova IM.
    Journal: Arkh Patol; 1990; 52(12):39-42. PubMed ID: 1965392.
    Abstract:
    Etiological factors and mechanisms of pretumorous and tumourous processes in the female genitalia are presented in light of current concept of viral cocarcinogenesis. The utility of cytoscreening for the detection of the papilloma-virus infection in the uterine cervix mucosa is founded. Detailed cytological characteristics of cells in the uterine cervix mucosa with a cytopathic effect (coilocytosis, the presence of two or many nuclei, vacuolisation of cytoplasm, nuclear atypia) are presented. A selective localization of the human papilloma virus in the transformation zone of the uterine cervix is determined. The frequency of cells with cytopathic effect is 80.2%.
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