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  • Title: Persistent portosystemic shunts after liver transplantation causing episodic hepatic encephalopathy.
    Author: Barritt AS, Fried MW, Hayashi PH.
    Journal: Dig Dis Sci; 2010 Jun; 55(6):1794-8. PubMed ID: 19655248.
    Abstract:
    We describe two cases of post liver transplant encephalopathy caused by persistent portosystemic shunts despite good graft function. Such recurrence of encephalopathy due to persistent shunting has not been reported in the deceased donor liver transplant literature. Our patients had episodic hepatic encephalopathy concordant with elevated serum ammonia levels due to well documented persistent portosystemic shunts. In one of our cases, the shunt was obliterated via coil embolization. This patient's encephalopathy resolved completely and has not recurred over seven months of follow up. The second patient has declined an intervention, but has remained symptom free on maintenance lactulose and rifaximin.
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