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  • Title: Optimization techniques in cardiac resynchronization therapy.
    Author: Fischer A.
    Journal: Future Cardiol; 2009 Jul; 5(4):355-65. PubMed ID: 19656060.
    Abstract:
    Cardiac resynchronization therapy improves symptoms and cardiac function, as well as reduces mortality in patients with progressive congestive heart failure, reduced left ventricular ejection fraction and a left bundle branch block on the surface electrocardiogram. As many as 30% of patients fail to have an adequate response. The interplay between the atrioventricular delay and the contribution of a properly timed atrial contraction to ventricular filling along with a properly timed sequence of activation of the right and left ventricular is crucial to maximizing the benefits of cardiac resynchronization therapy devices.
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