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  • Title: [Irvine Gass syndrome and central serous chorioretinopathy, pure coincidence or non fortuitous association? Report of three cases].
    Author: Boulanger G, Weber M.
    Journal: J Fr Ophtalmol; 2009 Oct; 32(8):566-71. PubMed ID: 19656588.
    Abstract:
    INTRODUCTION: Irvine-Gass syndrome is characterized by a cystoid macular edema after cataract surgery. The simultaneous or later appearance of a fluorescein leaking point associated with a central serous chorioretinopathy has never been published. MATERIALS AND METHODS: We report three patients presenting the association of Irvine-Gass syndrome and central serous chorioretinopathy. All had regular follow-up with fluorescein angiography and optical coherence tomography (OCT). OBSERVATIONS: The first two patients were 58 and 71 years old who developed Irvine-Gass edema several months after phakoemulsification. Treated with acetazolamide, they improved and OCT normalized. Several months later, they presented visual loss due to a macular serous retinal detachment. The angiography at that time found fluorescein leakage suggestive of central serous chorioretinopathy. The third case was a 63-year-old patient who presented the association of Irvine-Gass syndrome and supra-foveal central serous chorioretinopathy 3 months after phakoemulsification. DISCUSSION: Only a few cases of Irvine-Gass syndromes with serous retinal detachment on OCT have been reported in literature, but the absence of focal leakage on fluorescein angiography and the novelty of this association precluded the diagnosis of central serous chorioretinopathy. CONCLUSION: Even if Irvine-Gass syndrome and central serous chorioretinopathy are two well-known diseases, their association remains exceptional. Is this a new entity suggesting fragility of the retinal pigment epithelium as a common physiopathology?
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