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  • Title: Choroidal folds in acute Vogt-Koyanagi-Harada disease.
    Author: Zhao C, Zhang M, Wen X, Dong F, Han B, Du H.
    Journal: Ocul Immunol Inflamm; 2009; 17(4):282-8. PubMed ID: 19657984.
    Abstract:
    PURPOSE: To shed light on the clinical significance of choroidal folds (CFs) in acute Vogt-Koyanagi-Harada disease (VKH). METHODS: Twenty-three acute uveitic VKH patients diagnosed between October 2001 and January 2008 were reviewed retrospectively. RESULTS: Twelve (52%) patients had CFs; for patients with CFs, more had poor initial visual acuity (<or= 0.1 in either eye, p <.05), and more received immunomodulatory therapy (IMT) than those without CFs (p <.05). Patients without CFs had better best-corrected visual acuity (BCV) at final visit (p <.01). CONCLUSIONS: CFs are probably a sign of severe choroidal inflammation and associated with corticosteroid resistance and/or dependence, which indicates IMT.
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