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  • Title: [Antioxidant effect of berbamine].
    Author: Ju HS, Han ZW.
    Journal: Zhongguo Yao Li Xue Bao; 1990 Nov; 11(6):539-41. PubMed ID: 1966656.
    Abstract:
    The antiperoxidant action of berbamine (Ber) was demonstrated by colorimetric estimation of malondialdehyde (MDA) formation, and the scavenging effect of Ber on O2- was investigated by chemiluminescence method and ESR-spin trapping technique. Ber 11-100 mumol/L remarkably inhibited MDA formation induced by incubating mice liver homogenate at 37 degrees C with vibration for 1 h. Ber 1-100 mumol/L and 0.2-0.6 mmol/L effectively scavenged O2- in alkaline DMSO and xanthine/xanthine oxidase systems respectively. The results show that Ber is an antioxidant.
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