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  • Title: [Results of treatment for recurrent cancer of the uterine cervix].
    Author: Bazhenov AG, Guseĭnov KD, Khadzhimba AV, Baranov SB, Il'iashenko SA, Maksimov SIa.
    Journal: Vopr Onkol; 2009; 55(3):319-26. PubMed ID: 19670732.
    Abstract:
    The investigation involved 285 patients suffering from recurrences and distant metastases of uterine carcinoma cases of 24% of all (primary tumor). All recurrences generally occurred 12-20 months after the beginning of specialized therapy in 3.3-40%, with 78.3% detected within the first 24 months. Relapse was reported mostly in groups in which a single modality was used: surgery (32.4%) or radiotherapy (24.7%). Local recurrence rate for primary squamous cell tumor was 53.6%, adenocarcinoma - 6.3% and poorly-differentiated cell carcinoma - 4.9%. Complete regression of relapse following combined treatment was reported in 19% versus 14% and 4% after radiotherapy and chemotherapy, respectively. Moreover, more apparent responses were registered as a result of combinations of modalities (69%) as compared with 26% and 20% for radio- and chemotherapy, respectively.
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