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  • Title: Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified D-phenylalanine residues.
    Author: van der Knaap M, Engels E, Busscher HJ, Otero JM, Llamas-Saiz AL, van Raaij MJ, Mars-Groenendijk RH, Noort D, van der Marel GA, Overkleeft HS, Overhand M.
    Journal: Bioorg Med Chem; 2009 Sep 01; 17(17):6318-28. PubMed ID: 19674904.
    Abstract:
    The synthesis of new analogues of the cationic antimicrobial peptide gramicidin S, having a modified D-phenylalanine residue, their antibacterial properties against several gram positive and negative strains, as well as their hemolytic activity is reported.
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