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  • Title: The rostral and caudal ventrolateral medulla in young spontaneously hypertensive rats.
    Author: Smith JK, Barron KW.
    Journal: Brain Res; 1990 Jan 01; 506(1):153-8. PubMed ID: 1967962.
    Abstract:
    This study was designed to compare the cardiovascular influences of the rostral ventrolateral medulla (RVLM) and the caudal ventrolateral medulla (CVLM) in young (5-6 weeks) spontaneously hypertensive (SH) and normotensive Wistar-Kyoto (WKY) rats. SH and WKY groups had similar pressor and depressor responses to microinjection of L-glutamate into the RVLM and the CVLM, respectively. In addition the results of this study indicate a reduced tonic sympathoinhibitory function of the CVLM in young SH rats, which may contribute to the development of hypertension in the spontaneously hypertensive rat.
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