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  • Title: Night-time nasal ventilation in neuromuscular disease.
    Author: Heckmatt JZ, Loh L, Dubowitz V.
    Journal: Lancet; 1990 Mar 10; 335(8689):579-82. PubMed ID: 1968582.
    Abstract:
    14 patients, aged 2-28 years, with neuromuscular disorders and symptomatic sleep hypoventilation received night-time intermittent positive-pressure ventilation with a nasal mask. 9 were treated de novo and 5 had previously been maintained on a cuirass or iron lung. Nasal ventilation was very effective in 10 patients but was not tolerated in 4 of the 5 youngest patients. Nasal ventilation was preferable to other methods of ventilation because the system was non-invasive, quiet, portable, and easy to use and because it allowed considerable independence.
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