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  • Title: Ontogenesis of the electroretinogram in a precocial mammal, the guinea pig (Cavia porcellus).
    Author: Huang J, Wyse JP, Spira AW.
    Journal: Comp Biochem Physiol A Comp Physiol; 1990; 95(1):149-55. PubMed ID: 1968807.
    Abstract:
    1. Ontogenesis of the electroretinogram, the mass electrical response of the retina to flash light stimuli, was studied in the guinea pig (Cavia porcellus), a precocial species with visual function at birth. 2. a-Wave components, b-wave, oscillatory potentials, slow PIII, and c-wave responses to flash stimuli developed between 55 and 64 days of gestation (full term is 68-69 days). 3. a-Waves attributable to photoreceptor functions were fully mature at 60 days. 4. ERG development lagged behind the reported critical milestones in retinal development; its prenatal onset indicates that no history of light entrainment is required for initiation of a mature ERG response.
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