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  • Title: The changes in CiNa of sheep cardiac Purkinje fibres in hyperosmotic solutions.
    Author: Suleymanian MA, Ayrapetyan SN.
    Journal: Comp Biochem Physiol A Comp Physiol; 1990; 95(2):237-44. PubMed ID: 1968819.
    Abstract:
    1. The changes in intracellular sodium ion concentration (CiNa) of sheep cardiac Purkinje fibres in hyperosmotic solutions were studied using Na-sensitive liquid ion-exchanger microelectrodes. 2. CiNa was increased in hyperosmotic solutions containing different concentrations of sucrose from 0 to 300 mM. 3. The changes in resting membrane potential (RMP) in hyperosmotic solutions had no regularity. In most of the experiments there was hyperpolarization of the membrane but in a few cases a depolarization or no change of RMP were also observed. 4. The N-shape of I-V relations of the fibres became more pronounced in hyperosomotic solutions.
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