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  • Title: A case of S-100-positive juvenile xanthogranuloma: a longitudinal observation.
    Author: Yamamoto Y, Kadota M, Nishimura Y.
    Journal: Pediatr Dermatol; 2009; 26(4):475-6. PubMed ID: 19689531.
    Abstract:
    We present the case of a 9-month-old boy with yellow-brown papules that gradually increased in number over a period of 6 months without systemic involvement. Our case was clinicopathologically diagnosed as S-100-positive juvenile xanthogranuloma, and longitudinal observation revealed that strong S-100 reactivity disappeared in parallel with maturation of the lesions within 2 years after the initial diagnosis. These findings add to the complexity in cells of origin of this disorder.
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