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  • Title: [A case of stage IV AFP producing cecal cancer responding to mFOLFOX6 leading to a partial response].
    Author: Seshimo K, Yamashita Y, Oishi M, Yokomichi N, Ikeda H, Katoh H, Yamamura M, Kodera M, Maejima R, Kobayashi K, Takita K.
    Journal: Gan To Kagaku Ryoho; 2009 Aug; 36(8):1375-7. PubMed ID: 19692783.
    Abstract:
    We report a case of stage IV AFP producing cecal cancer responding to mFOLFOX6 leading to a partial response. The patient was a 72-year-old female with multiple liver metastases of cecal cancer. She underwent a right hemicolectomy and right salpingo-oophorectomy in a non-curative resection. Final findings revealed cecal cancer, type 3, 60 x 55 mm, pSI (right ovary), pN3, sH3, sP0, cM0, fStage IV, respectively. After surgery, chemotherapy with mFOLFOX6 was performed. After 4 courses, a significant tumor reduction (PR) was obtained. She died 1 year 2 months after surgery. This case suggests that chemotherapy with mFOLFOX6 is a potential regimen for AFP producing colon cancer.
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