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  • Title: [Advances of research on vascular endothelial growth factor receptors in epidermal neoplasm].
    Author: YANG P, ZHENG M.
    Journal: Zhejiang Da Xue Xue Bao Yi Xue Ban; 2009 Jul; 38(4):422-6. PubMed ID: 19693983.
    Abstract:
    Vascular endothelial growth factor (VEGF) exerts its biological functions by its specific VEGF receptors (VEGFRs), which includes VEGFR-1, VEGFR-2, VEGFR-3, neuropilin-1 and neuropilin-2. These VEGF receptors not only distribute in endothelial cells, but also in epidermal keratinocytes. VEGFRs may play a significant role in pathogenesis of the epidermal neoplasm and the VEGF-VEGFR signaling pathway may be a novel therapy target for neoplasm derived from epidermis.
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