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  • Title: Cycloartane triterpenes from dikamali, the gum resin of Gardenia gummifera and Gardenia lucida.
    Author: Kunert O, Sreekanth G, Babu GS, Rao BV, Radhakishan M, Kumar BR, Saf R, Rao AV, Schühly W.
    Journal: Chem Biodivers; 2009 Aug; 6(8):1185-92. PubMed ID: 19697336.
    Abstract:
    We report on the chemical investigation of dikamali gum, which is the resin of Gardenia gummifera and G. lucida (Rubiaceae). Six new cycloartane triterpenes, dikamaliartanes A-F (1-6, resp.), together with a known flavonoid (7), were isolated and identified by NMR spectroscopy. All six cycloartanes are characterized by an open A-ring with a free COOH group at C(3). In four of them, the C-atoms C(23)-C(27) form a 4-methylfuran-2-yl moiety. Bacterial assays using Staphylococcus aureus, Candida albicans, and Mycobacteria have been carried out but did not reveal significant activity.
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