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Title: Hippocampal volume and declarative memory function in combat-related PTSD. Author: Woodward SH, Kaloupek DG, Grande LJ, Stegman WK, Kutter CJ, Leskin L, Prestel R, Schaer M, Reiss AL, Eliez S. Journal: J Int Neuropsychol Soc; 2009 Nov; 15(6):830-9. PubMed ID: 19703322. Abstract: The proposition that declarative memory deficits are systematically related to smaller hippocampal volume was tested in a relatively large sample (n = 95) of U.S. military veterans with and without combat-related posttraumatic stress disorder. This correlative analysis was extended by including multiple measures of verbal and visual declarative memory and multiple memory-relevant regional brain volumes that had been shown to exhibit main effects of PTSD in prior work. Small-to-moderate effects were observed on verbal declarative memory in line with a recent meta-analysis; nevertheless, little or no evidence of systematic linear covariation between memory measures and brain volumes was observed.[Abstract] [Full Text] [Related] [New Search]