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  • Title: [Treatment of attack-like forms of schizophrenia in patients with residual cerebral organic insufficiency].
    Author: Avrutskiĭ GIa, Niss AI, Trubkovich MIa, Seid-Rzaev SM.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1990; 90(1):105-10. PubMed ID: 1970447.
    Abstract:
    As a result of studying 727 therapy courses conducted in 90 patients with attack-like schizophrenia, who suffered 294 attacks, it has been demonstrated that in case these patients have residual organocerebral failure, a special choice of "sparing" therapy is required. The treatment of these patients consists in the use of neuroleptics which do not provoke any marked extrapyramidal side effects (sonapax, eglonyl, leponex), tranquilzers and antidepressants possessing no cholinolytic effect (pyrazidol, nuredal). If the use of powerful antipsychotic neuroleptics and tricyclic antidepressants is required, it is indicated that they can be applied in the form of intravenous infusions. A modified method lying in the one-stage withdrawal of psychotropic agents turned out highly effective. Addition of resolving and dehydration remedies to psychopharmaco-therapy promoted neither enhancement of the drug efficacy nor minimization of the side effects.
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