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  • Title: Comparative assessment of siRNA and shRNA off target effects: what is slowing clinical development.
    Author: Rao DD, Senzer N, Cleary MA, Nemunaitis J.
    Journal: Cancer Gene Ther; 2009 Nov; 16(11):807-9. PubMed ID: 19713999.
    Abstract:
    This review considers comparisons of the off-target effects of siRNA to shRNA and their potential impact on the efficacy and toxicity of RNAi based therapeutics.
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