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  • Title: High-frequency rTMS over the supplementary motor area improves bradykinesia in Parkinson's disease: subanalysis of double-blind sham-controlled study.
    Author: Hamada M, Ugawa Y, Tsuji S, Effectiveness of rTMS on Parkinson's Disease Study Group, Japan.
    Journal: J Neurol Sci; 2009 Dec 15; 287(1-2):143-6. PubMed ID: 19720383.
    Abstract:
    A double-blind sham-controlled study demonstrated that high-frequency repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) provided relief of motor symptoms in patients with Parkinson's disease (PD). However, it remains to be determined which parkinsonian symptoms were improved by this treatment. Subanalysis of Unified Parkinson Disease Rating Scale revealed that rTMS over SMA significantly improved bradykinesia in PD. Results support the hypothesis that neuronal activity of SMA was profoundly associated with hypokinetic symptoms in PD.
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