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  • Title: [The plasma fibrinogen as a marker of subclinical carotid atherosclerosis].
    Author: Trappolini M, Stoppo M, Meggiorini M, Loguercio V, Fabiani O, Iannotta M, Negro A, Sebastianelli A, Proietta M, Del Porto F, Aliberti G.
    Journal: Recenti Prog Med; 2009; 100(7-8):352-5. PubMed ID: 19725475.
    Abstract:
    UNLABELLED: The aim of this study is to evaluate if plasma fibrinogen levels could correlate with carotid lesions. METHODS: We investigated the plasmatic levels of fibrinogen in 100 patients with asymptomatic carotid lesions, examined at ultrasound, and with at least one traditional cardiovascular risk factor. RESULTS: We found a significant correlation between plasma fibrinogen levels and severity of carotid lesions: intima-media thickness (p < 0.001), stenosis <70% (p < 0.002), stenosis 270% (p < 0.001). CONCLUSIONS: Beyond traditional cardiovascular risk factors, high plasmatic levels of fibrinogen significantly correlate with the thickness of carotid wall in asymptomatic subjects.
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