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  • Title: Ultrasonically assisted extraction of total phenols and flavonoids from Rhodiola rosea.
    Author: Staneva J, Todorova M, Neykov N, Evstatieva L.
    Journal: Nat Prod Commun; 2009 Jul; 4(7):935-8. PubMed ID: 19731597.
    Abstract:
    This work deals with ultrasonically assisted extraction (UAE) of biologically active compounds from rhizomes of Rhodiola rosea, a popular medicinal plant. The influence of temperature, type of solvent and solid/solvent ratio on the yield of total extracts, total phenols and flavonoids was established. The best extraction of total phenols and flavonoids was achieved by using 50% aqueous EtOH and MeOH, respectively. Five times increase of solid/solvent ratio (from 1:20 to 1:100 (w/v)) leads to slow increase of the yield of total phenols and flavonoids. The extraction effectiveness of conventional maceration with 50% EtOH and UAE performed for 1 h at 25 degrees C using the same solvent with respect of total phenols was comparable.
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