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  • Title: Chemical composition and antimicrobial activity of the essential oil of Anaphalis nubigena var. monocephala.
    Author: Joshi RK, Pande C, Mujawar MH, Kholkute SD.
    Journal: Nat Prod Commun; 2009 Jul; 4(7):993-6. PubMed ID: 19731610.
    Abstract:
    The essential oil composition of the aerial parts of Anaphalis nubigena DC. var. monocephala (DC.) C. B. Clarke collected from Pindari glacier at a height of 3300 m, was analyzed by using GC and GC/MS. Sixty components were identified, accounting for 95.9% of the total oil. The main constituents were alpha-guaiene (12.3%), gamma-muurolene (10.4%), gamma-cadinene (8.3%), alpha-muurolol (7.4%), alpha-gurjunene (6.0%) and alpha-bulnesene (5.8%). The oil was found to be rich in sesquiterpene hydrocarbons (60.1%). The oil was active against Escherichia coli (NCIM 2065) and Klebsiella pneumoniae (NCIM 2957), with MIC values of 125 microg/mL and 500 microg/mL, respectively.
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