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  • Title: The role of electrolytes on protein adsorption at a hydrophilic solid-water interface.
    Author: Wendorf JR, Radke CJ, Blanch HW.
    Journal: Colloids Surf B Biointerfaces; 2010 Jan 01; 75(1):100-6. PubMed ID: 19735992.
    Abstract:
    The adsorption of four proteins, RNase A, HEWL, BSA, and beta-Lac, was examined on the surface of a negatively charged SiO(2)/TiO(2) optical waveguide. The amount of adsorbed protein followed the salt series Mg(2+)>Li(+)>Na(+)>K(+) and for anions Cl(-)>Br(-)>I(-). This ordering was attributed to protein adsorption being primarily influenced by changes in hydrophobic interactions between the surface and the protein resulting from differences in water structure arising from the presence of electrolytes.
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