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  • Title: [The use of sucrose for the prevention of pain during venipuncture in neonates].
    Author: Giraldo Montoya I, Rodríguez Gázquez Mde L, Mejía Cadavid LA, Quirós Jaramillo A.
    Journal: Enferm Clin; 2009; 19(5):267-74. PubMed ID: 19736028.
    Abstract:
    OBJECTIVE: To evaluate the effectiveness of sucrose use in the prevention of pain during venipuncture in neonates. METHOD: Double blind randomized control trial. The population consisted of hospitalized neonates subjected to venipuncture. Sample size was calculated with a 95% confidence level, 80% power, minimum proportion of neonates with pain 40% in the study group and 70% in the control group. The minimum sample size was 49 newborns per group. Five minutes before venipuncture, the neonates received 1cc of oral solution of 12% sucrose (study group) or distilled water (control group). During the procedure the pain level was evaluated with NIPS (Neonatal Infant Pain Scale). A data base was created, and the information processed and analysed using the SPSS program. RESULTS: A total of 111 neonates were analysed, (55 in study group and 56 in control group). Bivariate analysis showed a smaller NIPS score in the group that received sucrose. Linear regression model explained that the significant variables for pain during the procedure were: hours since birth and the absence of non-nutritious suction, not being related to the sucrose administration. CONCLUSION: Neonates that received the oral solution of sucrose before venipuncture had an average pain score lower than the placebo controlled group.
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